Have you tried setting it to a lower resolution? You might also want to make sure you have the latest video drivers for your system - I know all kinds of strange things mysteriously get fixed by new video drivers.If Weldon were here, he'd probably suggest running dxdiag.exe and attaching the results here. That might turn up something useful.
By any chance, are you using a "Custom DPI Setting"?https://www.microsoft.com/resources/documentation/windows/xp/all/proddocs/en-us/display_use_large_or_small_fonts.mspxOne of our developers said that that has caused layout issues in the past.Also, have you tried running windowed rather than full screen?